Viruses, including the one responsible for COVID-19 (SARS-CoV-2), naturally evolve, leading to the emergence of "variants." These variations can influence transmissibility, treatment responsiveness and disease severity. Recently, a novel variant, BA.2.86, was identified in Denmark and Israel. Notably, it exhibits distinct genetic differences from earlier SARS-CoV-2 versions. This variant has been detected in the United States as well.